Can I use HRT if I have a history of endometriosis?

Using Hormone Replacement Therapy (HRT) with a history of endometriosis requires careful consideration.

HRT involving estrogen can potentially cause endometriosis to grow or recur in postmenopausal women and lead to health issues.

Endometriosis is a condition in which tissue like the lining inside the uterus (the endometrium) grows outside the uterus, causing pain and potentially leading to fertility problems.

Like uterine fibroids, the growth of endometriotic tissue is influenced by estrogen.

During the reproductive years, the fluctuation of estrogen levels plays a significant role in the development and progression of endometriosis.

After menopause, the body's natural estrogen levels decline, which usually leads to a decrease in endometriosis symptoms and the size of endometriotic lesions.

However, postmenopausal women who use estrogen supplementation, particularly without the balancing effect of progesterone, may experience growth or recurrence of endometriotic lesions due to the estrogen's stimulatory effects. This can lead to the re-emergence or worsening of endometriosis-related symptoms, including:

  • Pelvic pain: This can include chronic pain, pain during intercourse, and pain during bowel movements or urination.
  • Gastrointestinal issues: Symptoms like irritable bowel syndrome, such as bloating, constipation, and diarrhea, can occur.
  • Urinary problems: Including frequent urination, pain during urination, or even blood in the urine if endometriosis affects the urinary tract.

If you are postmenopausal with a history of endometriosis and you are considering taking HRT for relieving your menopausal discomforts, it's crucial to look for a hormone-free alternative approach.

NeuEve is hormone-free and is a safe natural product for relieving vaginal dryness. It has helped over 100,000 women to find relief from severe vaginal dryness, including those with the most severe type of vaginal dryness caused by pelvic radiation.

Disclaimer: This article is for information purposes only. It is about natural products, nutrients, and/or methods for managing discomforts associated with menopause or aging (not a true infection or disease). It is not medical advice for the treatment of any diseases.




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Dr. Renjie Chang

About the Author

Dr. Renjie Chang's medical and pharmaceutical experience:
- OB-GYN in the Peking Union Hospital in China
- a faculty member of OB-GYN at University of Oklahoma Health Sciences Center
- drug developer at the Abbott Laboratories in Chicago
- Founder of Lavax Inc, where she developed an innovative vaginal microbicide for preventing sexually transmitted disease with grants from NIH and Gates Foundation
- Founder of NeuEve, an all-natural women's health company